BDBM245576 US9428508, 31
SMILES: COc1cc(ccc1Nc1nc2NCC(C)c2c(Nc2ccccc2N(C)S(C)(=O)=O)n1)N1CCOCC1
InChI Key: InChIKey=GYQNTABGNFGHNP-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human)) | BDBM245576 (US9428508, 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd. US Patent | Assay Description To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... | US Patent US9428508 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R3S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM245576 (US9428508, 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <30 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd. US Patent | Assay Description To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... | US Patent US9428508 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R3S | |||||||||||
More data for this Ligand-Target Pair |