BDBM249184 US9457039, 7

SMILES: C[C@@]1(N)[C@H](O)[C@@H](CO)O[C@H]1c1cnn2c(N)ncnc12

InChI Key: InChIKey=BUPKMPMCEKZOJC-HGIWHZBTSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (NS5B) (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM249184 (US9457039, 7) Show SMILES C[C@@]1(N)[C@H](O)[C@@H](CO)O[C@H]1c1cnn2c(N)ncnc12 |r| Show InChI InChI=1S/C11H16N6O3/c1-11(13)7(19)6(3-18)20-8(11)5-2-16-17-9(5)14-4-15-10(17)12/h2,4,6-8,18-19H,3,13H2,1H3,(H2,12,14,15)/t6-,7-,8+,11-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	48
Merck Sharp & Dohme Corp. US Patent					Assay Description To measure cell-based anti-HCV activity of selected compounds of the present invention, replicon cells were seeded at 5000 cells/well in 96-well coll...				US Patent US9457039 (2016) BindingDB Entry DOI: 10.7270/Q2VD6XCW
					More data for this Ligand-Target Pair