BDBM24971 ({[(benzyloxy)carbonyl]amino}methyl)(methyl)sulfanylidenephosphinous acid::thiophosphinic acid derivative, 25
SMILES: CP(O)(=S)CNC(=O)OCc1ccccc1
InChI Key: InChIKey=VEJAHRSRJLDDTL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urea Amidohydrolase (Proteus vulgaris) | BDBM24971 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)sulfan...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.40E+4 | -6.73 | 1.58E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea Amidohydrolase (Bacillus pasteurii) | BDBM24971 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)sulfan...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.75E+4 | -6.59 | 1.12E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair |