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SMILES: FC(F)(F)c1ccnc(Oc2ccc3nc(ccc3c2)C(=O)N2CCNCC2)c1

InChI Key: InChIKey=NGASFLWLHULJGT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250848 (US9452986, 152) Show SMILES FC(F)(F)c1ccnc(Oc2ccc3nc(ccc3c2)C(=O)N2CCNCC2)c1 Show InChI InChI=1S/C20H17F3N4O2/c21-20(22,23)14-5-6-25-18(12-14)29-15-2-4-16-13(11-15)1-3-17(26-16)19(28)27-9-7-24-8-10-27/h1-6,11-12,24H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM250848 (US9452986, 152) Show SMILES FC(F)(F)c1ccnc(Oc2ccc3nc(ccc3c2)C(=O)N2CCNCC2)c1 Show InChI InChI=1S/C20H17F3N4O2/c21-20(22,23)14-5-6-25-18(12-14)29-15-2-4-16-13(11-15)1-3-17(26-16)19(28)27-9-7-24-8-10-27/h1-6,11-12,24H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116743 BindingDB Entry DOI: 10.7270/Q2BP06V9
					More data for this Ligand-Target Pair
Sodium channel protein type 7 subunit alpha (Homo sapiens (Human))	BDBM250848 (US9452986, 152) Show SMILES FC(F)(F)c1ccnc(Oc2ccc3nc(ccc3c2)C(=O)N2CCNCC2)c1 Show InChI InChI=1S/C20H17F3N4O2/c21-20(22,23)14-5-6-25-18(12-14)29-15-2-4-16-13(11-15)1-3-17(26-16)19(28)27-9-7-24-8-10-27/h1-6,11-12,24H,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116743 BindingDB Entry DOI: 10.7270/Q2BP06V9
					More data for this Ligand-Target Pair