BDBM253264 US9458171, 224

SMILES: Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)Nc1ccncc1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=SSKTTWGVMRGNEM-LJAQVGFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM253264 (US9458171, 224) Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)Nc1ccncc1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C32H24F9N3O4S/c33-22-8-10-24(11-9-22)49(46,47)29(14-17-44(19-29)28(45)43-23-12-15-42-16-13-23)20-4-6-21(7-5-20)30(31(36,37)38,32(39,40)41)48-18-25-26(34)2-1-3-27(25)35/h1-13,15-16H,14,17-19H2,(H,42,43,45)/t29-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintill...				US Patent US9458171 (2016) BindingDB Entry DOI: 10.7270/Q2NK3CZM
					More data for this Ligand-Target Pair