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SMILES: CCNC(=O)c1ccc(-c2ccc(F)c(c2)C2=C(CN3[C@@H](C)[C@H](OC3=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC(C)(C)CC2)c(c1)C(F)(F)F

InChI Key: InChIKey=AYKFBSZDGTVRCK-RQZFFVEVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254066   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM254066
PNG
(US9493430, 756)
Show SMILES CCNC(=O)c1ccc(-c2ccc(F)c(c2)C2=C(CN3[C@@H](C)[C@H](OC3=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC(C)(C)CC2)c(c1)C(F)(F)F |r,c:17|
Show InChI InChI=1S/C37H34F10N2O3/c1-5-48-32(50)21-6-8-27(29(15-21)37(45,46)47)20-7-9-30(38)28(14-20)26-10-11-34(3,4)17-23(26)18-49-19(2)31(52-33(49)51)22-12-24(35(39,40)41)16-25(13-22)36(42,43)44/h6-9,12-16,19,31H,5,10-11,17-18H2,1-4H3,(H,48,50)/t19-,31-/m0/s1
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PC cid
PC sid
UniChem
US Patent
n/an/a 5.90n/an/an/an/an/an/a



Chong Kun Dang Pharmaceutical Corp.

US Patent


Assay Description
As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...

US Patent US9493430 (2016)


BindingDB Entry DOI: 10.7270/Q2W37V7V
More data for this
Ligand-Target Pair