null
SMILES: C[C@]12C[C@H](F)[C@H]3[C@@H](CCc4cc(ccc34)C(=O)NCCCC(O)=O)[C@@H]1CC=C2c1cncc(F)c1
InChI Key: InChIKey=HBCIRHJTNBKRSH-JPBJBYSCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254838 (US9487554, 25) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16.8 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254838 (US9487554, 25) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 29.1 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair |