BDBM260025 US9512141, 23

SMILES: FC1(F)CN(C1)c1ncc(nc1OCC1CC1)C(=O)N1CCOC(=O)C1

InChI Key: InChIKey=DNODHRHZHANYEO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260025 (US9512141, 23) Show SMILES FC1(F)CN(C1)c1ncc(nc1OCC1CC1)C(=O)N1CCOC(=O)C1 Show InChI InChI=1S/C16H18F2N4O4/c17-16(18)8-22(9-16)13-14(26-7-10-1-2-10)20-11(5-19-13)15(24)21-3-4-25-12(23)6-21/h5,10H,1-4,6-9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512141 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VQ0
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260025 (US9512141, 23) Show SMILES FC1(F)CN(C1)c1ncc(nc1OCC1CC1)C(=O)N1CCOC(=O)C1 Show InChI InChI=1S/C16H18F2N4O4/c17-16(18)8-22(9-16)13-14(26-7-10-1-2-10)20-11(5-19-13)15(24)21-3-4-25-12(23)6-21/h5,10H,1-4,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	18.4	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512141 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VQ0
					More data for this Ligand-Target Pair