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SMILES: COc1cccc(c1)-c1nc(nn1CC(=O)NC(C)C)-c1ccc(CCN2CCOCC2)c(F)c1

InChI Key: InChIKey=IZOXTBJHBYLHBN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM260266 (US9522914, B-19) Show SMILES COc1cccc(c1)-c1nc(nn1CC(=O)NC(C)C)-c1ccc(CCN2CCOCC2)c(F)c1 Show InChI InChI=1S/C26H32FN5O3/c1-18(2)28-24(33)17-32-26(21-5-4-6-22(15-21)34-3)29-25(30-32)20-8-7-19(23(27)16-20)9-10-31-11-13-35-14-12-31/h4-8,15-16,18H,9-14,17H2,1-3H3,(H,28,33)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.4	25
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...				US Patent US9522914 (2016) BindingDB Entry DOI: 10.7270/Q2KS6PR7
					More data for this Ligand-Target Pair
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM260266 (US9522914, B-19) Show SMILES COc1cccc(c1)-c1nc(nn1CC(=O)NC(C)C)-c1ccc(CCN2CCOCC2)c(F)c1 Show InChI InChI=1S/C26H32FN5O3/c1-18(2)28-24(33)17-32-26(21-5-4-6-22(15-21)34-3)29-25(30-32)20-8-7-19(23(27)16-20)9-10-31-11-13-35-14-12-31/h4-8,15-16,18H,9-14,17H2,1-3H3,(H,28,33)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.4	4
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...				US Patent US9522914 (2016) BindingDB Entry DOI: 10.7270/Q2WM1CB9
					More data for this Ligand-Target Pair