null

SMILES: COc1ccc(CCn2ccc3c(Nc4nc(N[C@@H]5CCCC[C@@H]5N)ncc4C(N)=O)cccc23)cc1

InChI Key: InChIKey=MQTMHLJPZGLRHL-LADGPHEKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260710 (US9533989, 20 | US9533989, 35) Show SMILES COc1ccc(CCn2ccc3c(Nc4nc(N[C@@H]5CCCC[C@@H]5N)ncc4C(N)=O)cccc23)cc1 Show InChI InChI=1S/C28H33N7O2/c1-37-19-11-9-18(10-12-19)13-15-35-16-14-20-23(7-4-8-25(20)35)32-27-21(26(30)36)17-31-28(34-27)33-24-6-3-2-5-22(24)29/h4,7-12,14,16-17,22,24H,2-3,5-6,13,15,29H2,1H3,(H2,30,36)(H2,31,32,33,34)/t22-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260710 (US9533989, 20 | US9533989, 35) Show SMILES COc1ccc(CCn2ccc3c(Nc4nc(N[C@@H]5CCCC[C@@H]5N)ncc4C(N)=O)cccc23)cc1 Show InChI InChI=1S/C28H33N7O2/c1-37-19-11-9-18(10-12-19)13-15-35-16-14-20-23(7-4-8-25(20)35)32-27-21(26(30)36)17-31-28(34-27)33-24-6-3-2-5-22(24)29/h4,7-12,14,16-17,22,24H,2-3,5-6,13,15,29H2,1H3,(H2,30,36)(H2,31,32,33,34)/t22-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.67	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
					More data for this Ligand-Target Pair