BindingDB logo
myBDB logout

null

SMILES: COc1cccc(Cn2ccc3ccc(Nc4nc(N[C@@H]5CCCC[C@@H]5N)ncc4C(N)=O)cc23)c1

InChI Key: InChIKey=FRBQIMRFDJIQMQ-XZOQPEGZSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260773   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM260773
PNG
(US9533989, 84)
Show SMILES COc1cccc(Cn2ccc3ccc(Nc4nc(N[C@@H]5CCCC[C@@H]5N)ncc4C(N)=O)cc23)c1
Show InChI InChI=1S/C27H31N7O2/c1-36-20-6-4-5-17(13-20)16-34-12-11-18-9-10-19(14-24(18)34)31-26-21(25(29)35)15-30-27(33-26)32-23-8-3-2-7-22(23)28/h4-6,9-15,22-23H,2-3,7-8,16,28H2,1H3,(H2,29,35)(H2,30,31,32,33)/t22-,23+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 41.1n/an/an/an/an/an/a



Ziarco Pharma Ltd.

US Patent


Assay Description
The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...

US Patent US9533989 (2017)


BindingDB Entry DOI: 10.7270/Q2VQ31M7
More data for this
Ligand-Target Pair