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SMILES: COc1ccc(c(F)c1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1

InChI Key: InChIKey=CILWGFYXAHDZJT-IIBYNOLFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264857   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Pseudomonas aeruginosa)		BDBM264857
PNG
(US9718792, 59)
Show SMILES COc1ccc(c(F)c1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1 |r,t:17|
Show InChI InChI=1S/C21H23FN2O6S/c1-21(20(25)23-26,31(3,27)28)12-16-11-19(24-30-16)14-6-4-13(5-7-14)17-9-8-15(29-2)10-18(17)22/h4-10,16,26H,11-12H2,1-3H3,(H,23,25)/t16-,21-/m1/s1
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...

US Patent US9718792 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9T4Z
More data for this
Ligand-Target Pair