BDBM271025 7-(benzenesulfonyl)-4-(4,4-difluoropiperidin-1-yl)-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 142

SMILES: Cc1nc(N2CCC(F)(F)CC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=KUYSFGBZQSUGID-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM271025 (7-(benzenesulfonyl)-4-(4,4-difluoropiperidin-1-yl)...) Show SMILES Cc1nc(N2CCC(F)(F)CC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H19F2N5O2S/c1-11-22-13-14(17(23-11)25-9-7-18(19,20)8-10-25)24-16(21)15(13)28(26,27)12-5-3-2-4-6-12/h2-6,24H,7-10,21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair