BDBM271665 US10065941, Compound R-009::US9732060, Compound R-009
SMILES: COc1cc(Oc2ccc(cc2)\N=c2/[nH]c(=O)n([C@@H](C)[C@@H](C)C(O)=O)c(=O)n2Cc2ccc(Cl)cc2)ccn1
InChI Key:
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p2x3 (Homo sapiens (Human)) | BDBM271665 (US10065941, Compound R-009 | US9732060, Compound R...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.5 | n/a |
SHIONOGI & CO., LTD. US Patent | Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ... | US Patent US10065941 (2018) BindingDB Entry DOI: 10.7270/Q28P62J8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ratp2x3 (RAT) | BDBM271665 (US10065941, Compound R-009 | US9732060, Compound R...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SHIONOGI & CO., LTD. US Patent | Assay Description Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ... | US Patent US9732060 (2017) BindingDB Entry DOI: 10.7270/Q2ZC8506 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 3 (Homo sapiens (Human)) | BDBM271665 (US10065941, Compound R-009 | US9732060, Compound R...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
SHIONOGI & CO., LTD. US Patent | Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ... | US Patent US9732060 (2017) BindingDB Entry DOI: 10.7270/Q2ZC8506 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ratp2x3 (RAT) | BDBM271665 (US10065941, Compound R-009 | US9732060, Compound R...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SHIONOGI & CO., LTD. US Patent | Assay Description Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ... | US Patent US10065941 (2018) BindingDB Entry DOI: 10.7270/Q28P62J8 | |||||||||||
More data for this Ligand-Target Pair |