BDBM272134 (R)-2-(1,3-Dimethyl-1H-pyrazol-5-yl)-5-(3-fluoro-2- methylphenyl)-N-hydroxy-5,6-dihydro-4H- cyclopenta[d]thiazole-5-carboxamide::US10065948, 70::US10457675, Example 70

SMILES: Cc1cc(-c2nc3C[C@](Cc3s2)(C(=O)NO)c2cccc(F)c2C)n(C)n1

InChI Key: InChIKey=GABUTZUDMAPMJE-LJQANCHMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272134 ((R)-2-(1,3-Dimethyl-1H-pyrazol-5-yl)-5-(3-fluoro-2...) Show SMILES Cc1cc(-c2nc3C[C@](Cc3s2)(C(=O)NO)c2cccc(F)c2C)n(C)n1 |r| Show InChI InChI=1S/C19H19FN4O2S/c1-10-7-15(24(3)22-10)17-21-14-8-19(18(25)23-26,9-16(14)27-17)12-5-4-6-13(20)11(12)2/h4-7,26H,8-9H2,1-3H3,(H,23,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272134 ((R)-2-(1,3-Dimethyl-1H-pyrazol-5-yl)-5-(3-fluoro-2...) Show SMILES Cc1cc(-c2nc3C[C@](Cc3s2)(C(=O)NO)c2cccc(F)c2C)n(C)n1 |r| Show InChI InChI=1S/C19H19FN4O2S/c1-10-7-15(24(3)22-10)17-21-14-8-19(18(25)23-26,9-16(14)27-17)12-5-4-6-13(20)11(12)2/h4-7,26H,8-9H2,1-3H3,(H,23,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair