BDBM275833 5-chloro-N-(N,N- dimethylsulfamoyl)-2- fluoro-4-(2-phenoxy- ethoxy)benzamide::US10071957, Example 51

SMILES: CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCCOc2ccccc2)cc1F

InChI Key: InChIKey=ZTIIXMFEXYIVNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM275833 (5-chloro-N-(N,N- dimethylsulfamoyl)-2- fluoro-4-(2...) Show SMILES CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCCOc2ccccc2)cc1F Show InChI InChI=1S/C17H18ClFN2O5S/c1-21(2)27(23,24)20-17(22)13-10-14(18)16(11-15(13)19)26-9-8-25-12-6-4-3-5-7-12/h3-7,10-11H,8-9H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.62E+3	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...				US Patent US10071957 (2018) BindingDB Entry DOI: 10.7270/Q2J1056P
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