BDBM279242 US10035760, Example 67

SMILES: CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)c1ccccc1C)c1ccc2OCOc2c1

InChI Key: InChIKey=KSZYZGJQGLBAQA-FQEVSTJZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Envelope glycoprotein gp160 (Human immunodeficiency virus type 1 (isolate BRU/L...)	BDBM279242 (US10035760, Example 67) Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)c1ccccc1C)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C25H23F2N3O6S/c1-15-5-3-4-6-23(15)37(33,34)29-25(32)28-20(11-16-9-17(26)12-18(27)10-16)24(31)30(2)19-7-8-21-22(13-19)36-14-35-21/h3-10,12-13,20H,11,14H2,1-2H3,(H2,28,29,32)/t20-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
ViiV HEALTHCARE UK (NO. 5) LIMITED US Patent					Assay Description HIV cell culture assay¿MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...				US Patent US10035760 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RBW
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