BDBM27958 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol::Clenbuterol::Planipart
SMILES: CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
InChI Key: InChIKey=STJMRWALKKWQGH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM27958 (1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 570 | -8.43 | 1.30E+3 | n/a | 6.20 | n/a | n/a | 7.4 | 22 |
Intervet Innovation GmbH | Assay Description In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c... | J Med Chem 52: 1773-7 (2009) Article DOI: 10.1021/jm801211c BindingDB Entry DOI: 10.7270/Q2H993HR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM27958 (1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM | Bioorg Med Chem Lett 23: 5376-81 (2013) Article DOI: 10.1016/j.bmcl.2013.07.052 BindingDB Entry DOI: 10.7270/Q2F76GHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (BOVINE) | BDBM27958 (1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | J Med Chem 28: 1328-34 (1985) BindingDB Entry DOI: 10.7270/Q2HX1DZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADRB2 (BOVINE) | BDBM27958 (1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA | J Med Chem 29: 549-54 (1986) BindingDB Entry DOI: 10.7270/Q2PC33WN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADRB2 (BOVINE) | BDBM27958 (1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | J Med Chem 28: 1328-34 (1985) BindingDB Entry DOI: 10.7270/Q2HX1DZG | |||||||||||
More data for this Ligand-Target Pair |