BDBM280395 US10030012, Example 25::ethyl 4-{4-[5- (dimethyl-1,3- thiazol-5-yl)- 1H-pyrazol-1- yl]piperidin-1- yl}azepane-1- carboxylate

SMILES: CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1-c1sc(C)nc1C

InChI Key: InChIKey=GHSRIKLPZUXELX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM280395 (US10030012, Example 25 | ethyl 4-{4-[5- (dimethyl-...) Show SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1-c1sc(C)nc1C Show InChI InChI=1S/C22H33N5O2S/c1-4-29-22(28)26-12-5-6-18(8-15-26)25-13-9-19(10-14-25)27-20(7-11-23-27)21-16(2)24-17(3)30-21/h7,11,18-19H,4-6,8-10,12-15H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...				US Patent US10030012 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DTW
					More data for this Ligand-Target Pair