BDBM287743 US10085984, Example 121
SMILES: Fc1cc2nc(-c3cnnc4CCCc34)n(C3CC3)c2cc1F
InChI Key: InChIKey=PCQQHEQNQYZQRQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM287743![]() (US10085984, Example 121 | US11040034, Ex. No. 121) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals (Bermuda), Ltd. US Patent | Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t... | US Patent US10085984 (2018) BindingDB Entry DOI: 10.7270/Q2542QM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1 (Homo sapiens (Human)) | BDBM287743![]() (US10085984, Example 121 | US11040034, Ex. No. 121) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2 (Homo sapiens (Human)) | BDBM287743![]() (US10085984, Example 121 | US11040034, Ex. No. 121) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM287743![]() (US10085984, Example 121 | US11040034, Ex. No. 121) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals (Bermuda), Ltd. US Patent | Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t... | US Patent US10085984 (2018) BindingDB Entry DOI: 10.7270/Q2542QM2 | |||||||||||
More data for this Ligand-Target Pair |