BDBM292153 US10100057, Example 59::US10100057, Example 8::US9745310, Example 59

SMILES: Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1

InChI Key: InChIKey=YQVGHZZIEKWZGI-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 292153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	25
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US10100057 (2018) BindingDB Entry DOI: 10.7270/Q2028TKW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	25
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US10100057 (2018) BindingDB Entry DOI: 10.7270/Q2028TKW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US9745310 (2017) BindingDB Entry DOI: 10.7270/Q24T6MG4
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292153 (US10100057, Example 59 | US10100057, Example 8 | U...) Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US9745310 (2017) BindingDB Entry DOI: 10.7270/Q24T6MG4
					More data for this Ligand-Target Pair