null

SMILES: CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(CO)(CO)C1

InChI Key: InChIKey=ZHHQKJKPLDFJIV-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292588 ((S)-2-(3,3-bis(hydroxymethyl)azetidin-1-yl)-N-(2-(...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(CO)(CO)C1 |r| Show InChI InChI=1S/C28H35N7O3S/c1-4-33(5-2)19(3)13-29-27(38)20-11-23(31-25(12-20)34-15-28(16-34,17-36)18-37)21-14-30-35-9-8-22(32-26(21)35)24-7-6-10-39-24/h6-12,14,19,36-37H,4-5,13,15-18H2,1-3H3,(H,29,38)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292588 ((S)-2-(3,3-bis(hydroxymethyl)azetidin-1-yl)-N-(2-(...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(CO)(CO)C1 |r| Show InChI InChI=1S/C28H35N7O3S/c1-4-33(5-2)19(3)13-29-27(38)20-11-23(31-25(12-20)34-15-28(16-34,17-36)18-37)21-14-30-35-9-8-22(32-26(21)35)24-7-6-10-39-24/h6-12,14,19,36-37H,4-5,13,15-18H2,1-3H3,(H,29,38)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair