BindingDB logo
myBDB logout

null

SMILES: CCN(c1ccccc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1

InChI Key: InChIKey=MVOGRWWJJYSELN-IBGZPJMESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))		BDBM293668
PNG
(3-({[(1R)-6-[ethyl(phenyl)amino]-1,2,3,4-tetrahydr...)
Show SMILES CCN(c1ccccc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1 |r|
Show InChI InChI=1S/C25H27N3O2/c1-2-28(20-9-4-3-5-10-20)21-11-12-22-18(15-21)7-6-8-19(22)16-27-24-17-26-14-13-23(24)25(29)30/h3-5,9-15,17,19,27H,2,6-8,16H2,1H3,(H,29,30)/t19-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair