BDBM293683 3-{[(2-phenyl-5,6,7,8-tetrahydroquinolin-5-::US10106534, Example 25

SMILES: OC(=O)c1ccncc1NCC1CCCc2nc(ccc12)-c1ccccc1

InChI Key: InChIKey=QVAUPFRQYGGQRZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293683 (3-{[(2-phenyl-5,6,7,8-tetrahydroquinolin-5- | US10...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2nc(ccc12)-c1ccccc1 Show InChI InChI=1S/C22H21N3O2/c26-22(27)18-11-12-23-14-21(18)24-13-16-7-4-8-20-17(16)9-10-19(25-20)15-5-2-1-3-6-15/h1-3,5-6,9-12,14,16,24H,4,7-8,13H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293683 (3-{[(2-phenyl-5,6,7,8-tetrahydroquinolin-5- | US10...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2nc(ccc12)-c1ccccc1 Show InChI InChI=1S/C22H21N3O2/c26-22(27)18-11-12-23-14-21(18)24-13-16-7-4-8-20-17(16)9-10-19(25-20)15-5-2-1-3-6-15/h1-3,5-6,9-12,14,16,24H,4,7-8,13H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair