BDBM296074 2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 2::US10202381, Example 2::US10208039, Example 2::US10611763, Example 2::US10815234, Example 2

SMILES: Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12

InChI Key: InChIKey=OGJOQXKCDODHAH-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296074 (2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimi...) Show SMILES Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12 Show InChI InChI=1S/C16H12N4O2/c1-20-7-5-10-8-11(2-3-14(10)20)22-16-18-13-9-17-6-4-12(13)15(21)19-16/h2-9H,1H3,(H,18,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296074 (2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimi...) Show SMILES Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12 Show InChI InChI=1S/C16H12N4O2/c1-20-7-5-10-8-11(2-3-14(10)20)22-16-18-13-9-17-6-4-12(13)15(21)19-16/h2-9H,1H3,(H,18,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296074 (2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimi...) Show SMILES Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12 Show InChI InChI=1S/C16H12N4O2/c1-20-7-5-10-8-11(2-3-14(10)20)22-16-18-13-9-17-6-4-12(13)15(21)19-16/h2-9H,1H3,(H,18,19,21)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296074 (2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimi...) Show SMILES Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12 Show InChI InChI=1S/C16H12N4O2/c1-20-7-5-10-8-11(2-3-14(10)20)22-16-18-13-9-17-6-4-12(13)15(21)19-16/h2-9H,1H3,(H,18,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296074 (2-(1-methyl-1H-indol-5-yloxy)-pyrido[3,4- d]pyrimi...) Show SMILES Cn1ccc2cc(Oc3nc(O)c4ccncc4n3)ccc12 Show InChI InChI=1S/C16H12N4O2/c1-20-7-5-10-8-11(2-3-14(10)20)22-16-18-13-9-17-6-4-12(13)15(21)19-16/h2-9H,1H3,(H,18,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair