null

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1

InChI Key: InChIKey=PEMGIHULNQGIMC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296120 (4-[3-[4-(4-hydroxypyrido[3,4-d]pyrimidin- 2-yl)oxy...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1 Show InChI InChI=1S/C25H24N6O3/c1-29-12-13-31(16-23(29)32)19-5-3-4-18(14-19)30(2)17-6-8-20(9-7-17)34-25-27-22-15-26-11-10-21(22)24(33)28-25/h3-11,14-15H,12-13,16H2,1-2H3,(H,27,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296120 (4-[3-[4-(4-hydroxypyrido[3,4-d]pyrimidin- 2-yl)oxy...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1 Show InChI InChI=1S/C25H24N6O3/c1-29-12-13-31(16-23(29)32)19-5-3-4-18(14-19)30(2)17-6-8-20(9-7-17)34-25-27-22-15-26-11-10-21(22)24(33)28-25/h3-11,14-15H,12-13,16H2,1-2H3,(H,27,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296120 (4-[3-[4-(4-hydroxypyrido[3,4-d]pyrimidin- 2-yl)oxy...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1 Show InChI InChI=1S/C25H24N6O3/c1-29-12-13-31(16-23(29)32)19-5-3-4-18(14-19)30(2)17-6-8-20(9-7-17)34-25-27-22-15-26-11-10-21(22)24(33)28-25/h3-11,14-15H,12-13,16H2,1-2H3,(H,27,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296120 (4-[3-[4-(4-hydroxypyrido[3,4-d]pyrimidin- 2-yl)oxy...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1 Show InChI InChI=1S/C25H24N6O3/c1-29-12-13-31(16-23(29)32)19-5-3-4-18(14-19)30(2)17-6-8-20(9-7-17)34-25-27-22-15-26-11-10-21(22)24(33)28-25/h3-11,14-15H,12-13,16H2,1-2H3,(H,27,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296120 (4-[3-[4-(4-hydroxypyrido[3,4-d]pyrimidin- 2-yl)oxy...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)C(=O)C1 Show InChI InChI=1S/C25H24N6O3/c1-29-12-13-31(16-23(29)32)19-5-3-4-18(14-19)30(2)17-6-8-20(9-7-17)34-25-27-22-15-26-11-10-21(22)24(33)28-25/h3-11,14-15H,12-13,16H2,1-2H3,(H,27,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair