BDBM296135 2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)phenoxy]pyrido[3,4-d]pyrimidin- 4-ol::US10112940, Example 59::US10202381, Example 59::US10208039, Example 59::US10611763, Example 59::US10815234, Example 59

SMILES: CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=QMWFMZMUWRTMPB-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296135 (2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)ph...) Show SMILES CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C26H27N5O3/c1-3-18-4-5-20(16-24(18)31-12-14-33-15-13-31)30(2)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(32)29-26/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296135 (2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)ph...) Show SMILES CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C26H27N5O3/c1-3-18-4-5-20(16-24(18)31-12-14-33-15-13-31)30(2)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(32)29-26/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296135 (2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)ph...) Show SMILES CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C26H27N5O3/c1-3-18-4-5-20(16-24(18)31-12-14-33-15-13-31)30(2)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(32)29-26/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,29,32)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296135 (2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)ph...) Show SMILES CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C26H27N5O3/c1-3-18-4-5-20(16-24(18)31-12-14-33-15-13-31)30(2)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(32)29-26/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296135 (2-[4-(4-ethyl-N-methyl-3-morpholin-4- ylanilino)ph...) Show SMILES CCc1ccc(cc1N1CCOCC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C26H27N5O3/c1-3-18-4-5-20(16-24(18)31-12-14-33-15-13-31)30(2)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(32)29-26/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair