BDBM29663 MLS000573239::N-(1-benzyl-3-besyl-pyrrolo[3,2-b]quinoxalin-2-yl)propionamide::N-[1-(phenylmethyl)-3-(phenylsulfonyl)pyrrolo[3,2-b]quinoxalin-2-yl]propanamide::N-[1-benzyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-yl]propanamide::N-[3-(benzenesulfonyl)-1-(phenylmethyl)-2-pyrrolo[3,2-b]quinoxalinyl]propanamide::N-[3-(benzenesulfonyl)-1-benzylpyrrolo[3,2-b]quinoxalin-2-yl]propanamide::SMR000194740::cid_1348924

SMILES: CCC(=O)Nc1c(c2nc3ccccc3nc2n1Cc1ccccc1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=PCJFSQOYMRYINF-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29663 (MLS000573239 | N-(1-benzyl-3-besyl-pyrrolo[3,2-b]q...) Show SMILES CCC(=O)Nc1c(c2nc3ccccc3nc2n1Cc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H22N4O3S/c1-2-22(31)29-26-24(34(32,33)19-13-7-4-8-14-19)23-25(28-21-16-10-9-15-20(21)27-23)30(26)17-18-11-5-3-6-12-18/h3-16H,2,17H2,1H3,(H,29,31)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM29663 (MLS000573239 | N-(1-benzyl-3-besyl-pyrrolo[3,2-b]q...) Show SMILES CCC(=O)Nc1c(c2nc3ccccc3nc2n1Cc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H22N4O3S/c1-2-22(31)29-26-24(34(32,33)19-13-7-4-8-14-19)23-25(28-21-16-10-9-15-20(21)27-23)30(26)17-18-11-5-3-6-12-18/h3-16H,2,17H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29663 (MLS000573239 | N-(1-benzyl-3-besyl-pyrrolo[3,2-b]q...) Show SMILES CCC(=O)Nc1c(c2nc3ccccc3nc2n1Cc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H22N4O3S/c1-2-22(31)29-26-24(34(32,33)19-13-7-4-8-14-19)23-25(28-21-16-10-9-15-20(21)27-23)30(26)17-18-11-5-3-6-12-18/h3-16H,2,17H2,1H3,(H,29,31)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair