BDBM298353 (S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzoyl)-4-phenylpyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 3::US10611727, Example 3

SMILES: COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)c1ccccc1

InChI Key: InChIKey=MMJWMBIKUUAUNB-PVHODMMVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase-like (Human)	BDBM298353 ((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C32H33N3O5/c1-38-28-17-24(18-29(39-2)30(28)40-21-22-10-5-3-6-11-22)31(36)35-20-25(23-12-7-4-8-13-23)16-27(35)32(37)34-15-9-14-26(34)19-33/h3-8,10-13,17-18,25-27H,9,14-16,20-21H2,1-2H3/t25-,26+,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITAT DE BARCELONA; FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA; IPROTEOS S.L. US Patent					Assay Description POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...				US Patent US10611727 (2020)
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM298353 ((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C32H33N3O5/c1-38-28-17-24(18-29(39-2)30(28)40-21-22-10-5-3-6-11-22)31(36)35-20-25(23-12-7-4-8-13-23)16-27(35)32(37)34-15-9-14-26(34)19-33/h3-8,10-13,17-18,25-27H,9,14-16,20-21H2,1-2H3/t25-,26+,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITAT DE BARCELONA; FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA); IPROTEOS S.L. US Patent					Assay Description POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...				US Patent US10125097 (2018) BindingDB Entry DOI: 10.7270/Q22J6DX3
					More data for this Ligand-Target Pair