null

SMILES: C[C@@H]1CN(Cc2cc(ccc2C)C(CCc2cnn(C)n2)CC(O)=O)S(=O)(=O)c2ccccc2O1

InChI Key: InChIKey=UEORTKJCUOEYPP-QSVWIEALSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 [321-609] (Homo sapiens (Human))	BDBM304825 (5-(2-Methyl-2H-1,2,3-triazol-4-yl)-3-(4-methyl-3-(...) Show SMILES C[C@@H]1CN(Cc2cc(ccc2C)C(CCc2cnn(C)n2)CC(O)=O)S(=O)(=O)c2ccccc2O1 |r| Show InChI InChI=1S/C25H30N4O5S/c1-17-8-9-19(20(13-25(30)31)10-11-22-14-26-28(3)27-22)12-21(17)16-29-15-18(2)34-23-6-4-5-7-24(23)35(29,32)33/h4-9,12,14,18,20H,10-11,13,15-16H2,1-3H3,(H,30,31)/t18-,20?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent					Assay Description 100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...				US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17
					More data for this Ligand-Target Pair
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM304825 (5-(2-Methyl-2H-1,2,3-triazol-4-yl)-3-(4-methyl-3-(...) Show SMILES C[C@@H]1CN(Cc2cc(ccc2C)C(CCc2cnn(C)n2)CC(O)=O)S(=O)(=O)c2ccccc2O1 |r| Show InChI InChI=1S/C25H30N4O5S/c1-17-8-9-19(20(13-25(30)31)10-11-22-14-26-28(3)27-22)12-21(17)16-29-15-18(2)34-23-6-4-5-7-24(23)35(29,32)33/h4-9,12,14,18,20H,10-11,13,15-16H2,1-3H3,(H,30,31)/t18-,20?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent					Assay Description NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...				US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17
					More data for this Ligand-Target Pair