BindingDB logo
myBDB logout

null

SMILES: CN(C)S(=O)(=O)NCC(=O)Nc1cc(c(Cl)cn1)-c1ccc2ncn(CC3CCOCC3)c2c1

InChI Key: InChIKey=PXMPXYIXNJCMSY-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307993   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 9


(Homo sapiens (Human))		BDBM307993
PNG
( N-{5-chloro-4-[1-(tetrahydro-2H-pyran-4-ylmethyl)...)
Show SMILES CN(C)S(=O)(=O)NCC(=O)Nc1cc(c(Cl)cn1)-c1ccc2ncn(CC3CCOCC3)c2c1
Show InChI InChI=1S/C22H27ClN6O4S/c1-28(2)34(31,32)26-12-22(30)27-21-10-17(18(23)11-24-21)16-3-4-19-20(9-16)29(14-25-19)13-15-5-7-33-8-6-15/h3-4,9-11,14-15,26H,5-8,12-13H2,1-2H3,(H,24,27,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 230n/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...

US Patent US9650358 (2017)


BindingDB Entry DOI: 10.7270/Q2057J0M
More data for this
Ligand-Target Pair