BindingDB logo
myBDB logout

null

SMILES: OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc2cccnc12

InChI Key: InChIKey=JBBUNYHTLRNBRT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310188   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM310188
PNG
(1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...)
Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc2cccnc12
Show InChI InChI=1S/C25H28N4O2/c30-22(16-27-12-10-19-5-1-2-6-21(19)15-27)17-29-14-13-28(18-24(29)31)23-9-3-7-20-8-4-11-26-25(20)23/h1-9,11,22,30H,10,12-18H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent


Assay Description
The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....

US Patent US10150758 (2018)


BindingDB Entry DOI: 10.7270/Q2W95C8T
More data for this
Ligand-Target Pair