BDBM310922 ((6-Bromo-2-(Hydroxymethyl)Benzo[b]Thiophen-5-yl)Difluoromethyl)Phosphonate::US10150787, Example 5

SMILES: OCc1cc2cc(c(Br)cc2s1)C(F)(F)P(O)(O)=O

InChI Key: InChIKey=WWIKGONDKIGLQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM310922 (((6-Bromo-2-(Hydroxymethyl)Benzo[b]Thiophen-5-yl)D...) Show SMILES OCc1cc2cc(c(Br)cc2s1)C(F)(F)P(O)(O)=O Show InChI InChI=1S/C10H8BrF2O4PS/c11-8-3-9-5(1-6(4-14)19-9)2-7(8)10(12,13)18(15,16)17/h1-3,14H,4H2,(H2,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...				US Patent US10150787 (2018) BindingDB Entry DOI: 10.7270/Q2QJ7KC8
					More data for this Ligand-Target Pair