BDBM311425 US10155764, Example 16B

SMILES: CN(C)[C@@H]1CCC[C@@H]1Nc1nn(C)c(=O)c2cccnc12

InChI Key: InChIKey=LHAAQQYGFUKSFC-NWDGAFQWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311425 (US10155764, Example 16B) Show SMILES CN(C)[C@@H]1CCC[C@@H]1Nc1nn(C)c(=O)c2cccnc12 |r| Show InChI InChI=1S/C15H21N5O/c1-19(2)12-8-4-7-11(12)17-14-13-10(6-5-9-16-13)15(21)20(3)18-14/h5-6,9,11-12H,4,7-8H2,1-3H3,(H,17,18)/t11-,12+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair