BDBM312212 US9604926, Compound CM-624::US9724435, Compound CM624

SMILES: Fc1ccc(N2CCN(CCCCn3c4ccccc4oc3=O)CC2)c(F)c1

InChI Key: InChIKey=DDIWZITUFBYTBP-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-2 receptor (Rattus norvegicus (Rat))	BDBM312212 (US9604926, Compound CM-624 | US9724435, Compound C...) Show SMILES Fc1ccc(N2CCN(CCCCn3c4ccccc4oc3=O)CC2)c(F)c1 Show InChI InChI=1S/C21H23F2N3O2/c22-16-7-8-18(17(23)15-16)25-13-11-24(12-14-25)9-3-4-10-26-19-5-1-2-6-20(19)28-21(26)27/h1-2,5-8,15H,3-4,9-14H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Mus musculus (Mouse))	BDBM312212 (US9604926, Compound CM-624 | US9724435, Compound C...) Show SMILES Fc1ccc(N2CCN(CCCCn3c4ccccc4oc3=O)CC2)c(F)c1 Show InChI InChI=1S/C21H23F2N3O2/c22-16-7-8-18(17(23)15-16)25-13-11-24(12-14-25)9-3-4-10-26-19-5-1-2-6-20(19)28-21(26)27/h1-2,5-8,15H,3-4,9-14H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse))	BDBM312212 (US9604926, Compound CM-624 | US9724435, Compound C...) Show SMILES Fc1ccc(N2CCN(CCCCn3c4ccccc4oc3=O)CC2)c(F)c1 Show InChI InChI=1S/C21H23F2N3O2/c22-16-7-8-18(17(23)15-16)25-13-11-24(12-14-25)9-3-4-10-26-19-5-1-2-6-20(19)28-21(26)27/h1-2,5-8,15H,3-4,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM312212 (US9604926, Compound CM-624 | US9724435, Compound C...) Show SMILES Fc1ccc(N2CCN(CCCCn3c4ccccc4oc3=O)CC2)c(F)c1 Show InChI InChI=1S/C21H23F2N3O2/c22-16-7-8-18(17(23)15-16)25-13-11-24(12-14-25)9-3-4-10-26-19-5-1-2-6-20(19)28-21(26)27/h1-2,5-8,15H,3-4,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair