BDBM313799 US10167292, Example 43
SMILES: C[C@H](NC(=O)c1ccc2-c3c(C)nnn3CCN(c3ccccc3)c2c1)c1ccc(F)cc1
InChI Key: InChIKey=SNGNCZZQXBBFQK-KRWDZBQOSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 2 [91-163] (Homo sapiens (Human)) | BDBM313799 (US10167292, Example 43) | GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Catalyst Therapeutics Pty Ltd. US Patent | Assay Description BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p... | US Patent US10167292 (2019) BindingDB Entry DOI: 10.7270/Q2765HFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [368-440] (Homo sapiens (Human)) | BDBM313799 (US10167292, Example 43) | GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Catalyst Therapeutics Pty Ltd. US Patent | Assay Description BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p... | US Patent US10167292 (2019) BindingDB Entry DOI: 10.7270/Q2765HFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [75-147] (Homo sapiens (Human)) | BDBM313799 (US10167292, Example 43) | GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Catalyst Therapeutics Pty Ltd. US Patent | Assay Description BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p... | US Patent US10167292 (2019) BindingDB Entry DOI: 10.7270/Q2765HFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [364-436] (Homo sapiens (Human)) | BDBM313799 (US10167292, Example 43) | GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Catalyst Therapeutics Pty Ltd. US Patent | Assay Description BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p... | US Patent US10167292 (2019) BindingDB Entry DOI: 10.7270/Q2765HFS | |||||||||||
More data for this Ligand-Target Pair |