null
SMILES: CC(=O)\N=c1/sc(nn1C)S(N)(=O)=O
InChI Key: InChIKey=FLOSMHQXBMRNHR-DAXSKMNVSA-N
PDB links: 7 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM315269 (US10172837, Methazolamide) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Naia Metabolic, Inc. US Patent | Assay Description Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ... | US Patent US10172837 (2019) BindingDB Entry DOI: 10.7270/Q2VT1V5M | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |