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SMILES: Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(Cl)c1

InChI Key: InChIKey=IWZHMHULYNVWPG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM316104 (US9616064, Compound 30c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C20H16ClN5O/c21-14-4-1-3-13(11-14)12-24-19(27)16-5-2-6-17-15(16)8-10-26(17)18-7-9-23-20(22)25-18/h1-11H,12H2,(H,24,27)(H2,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent									US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316104 (US9616064, Compound 30c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C20H16ClN5O/c21-14-4-1-3-13(11-14)12-24-19(27)16-5-2-6-17-15(16)8-10-26(17)18-7-9-23-20(22)25-18/h1-11H,12H2,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair