BDBM316183 N-(4-methoxy-3-nitrophenyl)-6-(2-methoxyphenyl)pyrimidin-4-amine::US10294218, Example 11::US9617225, Example 11

SMILES: COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)[N+]([O-])=O)ncn1

InChI Key: InChIKey=ZHFNQFDJLZJRPE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 316183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316183 (N-(4-methoxy-3-nitrophenyl)-6-(2-methoxyphenyl)pyr...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)[N+]([O-])=O)ncn1 Show InChI InChI=1S/C18H16N4O4/c1-25-16-6-4-3-5-13(16)14-10-18(20-11-19-14)21-12-7-8-17(26-2)15(9-12)22(23)24/h3-11H,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human))	BDBM316183 (N-(4-methoxy-3-nitrophenyl)-6-(2-methoxyphenyl)pyr...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)[N+]([O-])=O)ncn1 Show InChI InChI=1S/C18H16N4O4/c1-25-16-6-4-3-5-13(16)14-10-18(20-11-19-14)21-12-7-8-17(26-2)15(9-12)22(23)24/h3-11H,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human))	BDBM316183 (N-(4-methoxy-3-nitrophenyl)-6-(2-methoxyphenyl)pyr...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)[N+]([O-])=O)ncn1 Show InChI InChI=1S/C18H16N4O4/c1-25-16-6-4-3-5-13(16)14-10-18(20-11-19-14)21-12-7-8-17(26-2)15(9-12)22(23)24/h3-11H,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316183 (N-(4-methoxy-3-nitrophenyl)-6-(2-methoxyphenyl)pyr...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)[N+]([O-])=O)ncn1 Show InChI InChI=1S/C18H16N4O4/c1-25-16-6-4-3-5-13(16)14-10-18(20-11-19-14)21-12-7-8-17(26-2)15(9-12)22(23)24/h3-11H,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair