BDBM317604 US9624199, 14::{6-[(1-Methoxybutan-2-yl)amino]pyridin-3-yl}[(3R)-3-methyl-1,4′-bipiperidin-1′-yl]methanone

SMILES: CCC(COC)Nc1ccc(cn1)C(=O)N1CCC(CC1)N1CCC[C@@H](C)C1

InChI Key: InChIKey=MVHLBLFCGGJBTH-DUSLRRAJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM317604 (US9624199, 14 | {6-[(1-Methoxybutan-2-yl)amino]pyr...) Show SMILES CCC(COC)Nc1ccc(cn1)C(=O)N1CCC(CC1)N1CCC[C@@H](C)C1 |r| Show InChI InChI=1S/C22H36N4O2/c1-4-19(16-28-3)24-21-8-7-18(14-23-21)22(27)25-12-9-20(10-13-25)26-11-5-6-17(2)15-26/h7-8,14,17,19-20H,4-6,9-13,15-16H2,1-3H3,(H,23,24)/t17-,19?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description To prepare cell membranes with human α1- and α2-adrenergic receptors, CHO cells stably overexpressing α1- and α2-adrenergic recep...				US Patent US9624199 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6VB7
					More data for this Ligand-Target Pair