BDBM317607 US9624199, 17::[3-(Cyclopropylmethoxy)-1,4′-bipiperidin-1′-yl][2-(morpholin-4-yl)pyrimidin-5-yl]methanone

SMILES: O=C(N1CCC(CC1)N1CCCC(C1)OCC1CC1)c1cnc(nc1)N1CCOCC1

InChI Key: InChIKey=NBHMDJXGHOWFQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM317607 (US9624199, 17 | [3-(Cyclopropylmethoxy)-1,4′...) Show SMILES O=C(N1CCC(CC1)N1CCCC(C1)OCC1CC1)c1cnc(nc1)N1CCOCC1 Show InChI InChI=1S/C23H35N5O3/c29-22(19-14-24-23(25-15-19)27-10-12-30-13-11-27)26-8-5-20(6-9-26)28-7-1-2-21(16-28)31-17-18-3-4-18/h14-15,18,20-21H,1-13,16-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description To prepare cell membranes with human α1- and α2-adrenergic receptors, CHO cells stably overexpressing α1- and α2-adrenergic recep...				US Patent US9624199 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6VB7
					More data for this Ligand-Target Pair