null
SMILES: CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1
InChI Key: InChIKey=UNUPAGHCXHMCOJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835H] (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM319752 (US10174013, Example 1A | US10174013, Example 1X | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a |
SELVITA S.A. US Patent | Assay Description Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s... | US Patent US10174013 (2019) BindingDB Entry DOI: 10.7270/Q2QR5069 | |||||||||||
More data for this Ligand-Target Pair |