BDBM320349 4-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-5H-pyrido[3,2-b]indol-7-yl}-1λ6,4-thiomorpholine-1,1-dione::US10174024, Example 67::US10174024, Example 68

SMILES: Cc1n[nH]n(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1cc(ccc21)N1CCS(=O)(=O)CC1

InChI Key: InChIKey=NLLQAOBHTJMLEA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320349 (4-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-3-[...) Show SMILES Cc1n[nH]n(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1cc(ccc21)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C30H32FN7O3S/c1-19-29(36(2)35-34-19)21-16-26-27(33-18-21)23-6-5-22(37-10-14-42(39,40)15-11-37)17-25(23)38(26)30(20-7-12-41-13-8-20)28-24(31)4-3-9-32-28/h3-6,9,16-18,20,30H,7-8,10-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320349 (4-{5-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-3-[...) Show SMILES Cc1n[nH]n(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1cc(ccc21)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C30H32FN7O3S/c1-19-29(36(2)35-34-19)21-16-26-27(33-18-21)23-6-5-22(37-10-14-42(39,40)15-11-37)17-25(23)38(26)30(20-7-12-41-13-8-20)28-24(31)4-3-9-32-28/h3-6,9,16-18,20,30H,7-8,10-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair