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SMILES: C\C=C\Cn1cc(-c2ccc(cc2)C(C)(C)O)c2cc[nH]c2c1=O

InChI Key: InChIKey=HCKOJNDQXGXWSS-SNAWJCMRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 9 [134-239]


(Homo sapiens (Human))		BDBM321402
PNG
(6-[(E)-but-2-enyl]-4-[4-(1-hydroxy-1-methyl-ethyl)...)
Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(C)(C)O)c2cc[nH]c2c1=O
Show InChI InChI=1S/C20H22N2O2/c1-4-5-12-22-13-17(16-10-11-21-18(16)19(22)23)14-6-8-15(9-7-14)20(2,3)24/h4-11,13,21,24H,12H2,1-3H3/b5-4+
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...

US Patent US10183009 (2019)


BindingDB Entry DOI: 10.7270/Q2125VRQ
More data for this
Ligand-Target Pair