BDBM321428 1-[4-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl]-2-chloro-benzoyl]piperidine-4-carboxylic acid::US10183009, Example 112

SMILES: C\C=C\Cn1cc(-c2ccc(C(=O)N3CCC(CC3)C(O)=O)c(Cl)c2)c2cc(C)[nH]c2c1=O

InChI Key: InChIKey=UFPCMDICDNXCKT-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRD9 (aa 134-239) (Homo sapiens (Human))	BDBM321428 (1-[4-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCC(CC3)C(O)=O)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H26ClN3O4/c1-3-4-9-29-14-20(19-12-15(2)27-22(19)24(29)31)17-5-6-18(21(26)13-17)23(30)28-10-7-16(8-11-28)25(32)33/h3-6,12-14,16,27H,7-11H2,1-2H3,(H,32,33)/b4-3+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair