null

SMILES: COc1cc(CCNC(=O)[C@H]2CNCCO2)c(Cl)cc1NC(=O)Nc1cnc(cn1)C#N

InChI Key: InChIKey=ACJFENMVUGUECR-QGZVFWFLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM323153 (US9630931, Example 15) Show SMILES COc1cc(CCNC(=O)[C@H]2CNCCO2)c(Cl)cc1NC(=O)Nc1cnc(cn1)C#N |r| Show InChI InChI=1S/C20H22ClN7O4/c1-31-16-6-12(2-3-24-19(29)17-10-23-4-5-32-17)14(21)7-15(16)27-20(30)28-18-11-25-13(8-22)9-26-18/h6-7,9,11,17,23H,2-5,10H2,1H3,(H,24,29)(H2,26,27,28,30)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
SENTINEL ONCOLOGY LIMITED US Patent					Assay Description Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...				US Patent US9630931 (2017) BindingDB Entry DOI: 10.7270/Q29C70J1
					More data for this Ligand-Target Pair