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SMILES: CCN(Cc1ccc(cc1)[C@H]1COc2ccccc2O1)Cc1cccc(c1)C(O)=O

InChI Key: InChIKey=VRGOUWKXZLTGEP-XMMPIXPASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327149   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM327149
PNG
(3-{[{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]...)
Show SMILES CCN(Cc1ccc(cc1)[C@H]1COc2ccccc2O1)Cc1cccc(c1)C(O)=O |r|
Show InChI InChI=1S/C25H25NO4/c1-2-26(16-19-6-5-7-21(14-19)25(27)28)15-18-10-12-20(13-11-18)24-17-29-22-8-3-4-9-23(22)30-24/h3-14,24H,2,15-17H2,1H3,(H,27,28)/t24-/m1/s1
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US Patent
n/an/a 0.550n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...

US Patent US9662339 (2017)


BindingDB Entry DOI: 10.7270/Q2GT5Q8D
More data for this
Ligand-Target Pair