BDBM32760 3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethyl)-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine::3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethyl)triazolo[4,5-d]pyrimidin-7-amine::3-[(2-chlorophenyl)methyl]-N-[2-(4-morpholinyl)ethyl]-7-triazolo[4,5-d]pyrimidinamine::MLS000034167::SMR000007989::[3-(2-Chloro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-morpholin-4-yl-ethyl)-amine::[3-(2-chlorobenzyl)triazolo[4,5-d]pyrimidin-7-yl]-(2-morpholinoethyl)amine::cid_653228

SMILES: Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12

InChI Key: InChIKey=JTJMXJYSNATRPM-UHFFFAOYSA-N

Data: 2 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 32760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	23
PCMD Curated by PubChem BioAssay					Assay Description Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2H993J6
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2RJ4GWX
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM32760 (3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethy...) Show SMILES Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C17H20ClN7O/c18-14-4-2-1-3-13(14)11-25-17-15(22-23-25)16(20-12-21-17)19-5-6-24-7-9-26-10-8-24/h1-4,12H,5-11H2,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair