BDBM328410 5-bromo-1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-3-methyl-1H-indole::US9663498, Example 62

SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C)c2cc(Br)ccc12

InChI Key: InChIKey=AOAOBXLWOLIEQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM328410 (5-bromo-1-((4-methoxy-3-(piperazin-1-yl)phenyl)sul...) Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C)c2cc(Br)ccc12 Show InChI InChI=1S/C20H22BrN3O3S/c1-14-13-24(18-5-3-15(21)11-17(14)18)28(25,26)16-4-6-20(27-2)19(12-16)23-9-7-22-8-10-23/h3-6,11-13,22H,7-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...				US Patent US9663498 (2017) BindingDB Entry DOI: 10.7270/Q22N54C8
					More data for this Ligand-Target Pair