BDBM330177 4-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]benzamide::US9663530, Example 21

SMILES: Clc1ccc(cc1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1

InChI Key: InChIKey=RQJHGWLDRXIGLH-IEBWSBKVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330177 (4-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C19H19ClN2O2/c20-15-5-3-14(4-6-15)18(23)22-16-7-1-13(2-8-16)9-19-10-17(11-24-19)21-12-19/h1-8,17,21H,9-12H2,(H,22,23)/t17-,19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.6	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330177 (4-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C19H19ClN2O2/c20-15-5-3-14(4-6-15)18(23)22-16-7-1-13(2-8-16)9-19-10-17(11-24-19)21-12-19/h1-8,17,21H,9-12H2,(H,22,23)/t17-,19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair